Apelin and APJ, a novel critical factor and therapeutic target for atherosclerosis
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چکیده
منابع مشابه
Apelin and APJ, a novel critical factor and therapeutic target for atherosclerosis.
Apelin is a bioactive peptide discovered recently that has been proved to be an endogenous ligand of the APJ receptor. Apelin and APJ are widely distributed in the central nervous system and peripheral tissues. Researches have confirmed that apelin/APJ involved in a wide range of physiological and pathological functions in the cardiovascular system. Investigations indicated that apelin is a nov...
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Apelin is a recently discovered bioactive peptide, known to be an endogenous high-affinity ligandfor the previously orphan G protein-coupled receptor APJ. Apelin/APJ as a novel signaling pathwayhas been shown to play many crucial roles in cardiovascular function, blood pressure regulation, fluidhomeostasis, feeding behavior, obesity, type 2 diabetes mellitus, adipoinsular axis regulation, cellp...
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ژورنال
عنوان ژورنال: Acta Biochimica et Biophysica Sinica
سال: 2013
ISSN: 1745-7270,1672-9145
DOI: 10.1093/abbs/gmt040